Esophageal Cancer Treatment
Cancer that forms in tissues lining the esophagus (the muscular tube through
which food passes from the throat to the stomach). Two types of esophageal
cancer are squamous cell carcinoma (cancer that begins in flat cells lining the
esophagus) and adenocarcinoma (cancer that begins in cells that make and
release mucus and other fluids). Esophageal cancer has been categorized into
two types that include :
Adenocarcinoma
: This type of
esophageal cancer starts in the glandular tissue in the lower part of the
esophagus. The stomach and the esophagus appear together in this lower part of
esophagus.
Squamous
Cell Carcinoma : Squamous
cell carcinoma begins in the squamous cells lining the esophagus. This type of
esophageal cancer typically occurs in the middle and upper part of the
esophagus.
Early esophageal cancer
usually does not cause symptoms. However, as the cancer grows, symptoms may
include painful or difficulty in swallowing, weight loss and coughing up blood.
Risk factors for developing esophageal cancer include:
·
Smoking
·
Heavy
Drinking
·
Damage
from acid reflux
·
Frequent
choking while eating
·
Chest
burning, pain or pressure
Stages of
Esophageal Cancer
·
Stage 0: In this stage, the
abnormal or unusual cells can only be seen in the layer of cells lining the
esophagus.
·
Stage 1: The first stage is
marked by the presence of cancer cells in the layer of cells lining the
esophagus.
·
Stage 2: In the second
stage, the cancer has reached to the outer wall of the esophagus or to the
muscle layer of the esophagus. Also these cancer cells may have invaded 1-2
surrounding lymph nodes.
·
Stage 3: The third stage is
marked by the spread of the cancer into the connective tissue wall or deep into
the inner muscle layer. Also this cancer has spread to more lymph nodes close
to esophagus and they may also spread beyond esophagus in the surrounding
organ.
·
Stage 4: This is
considered as the advanced stage of esophageal cancer. Now the cancer has
spread to lymph nodes far away from the esophagus or to different organs.
DIAGNOSIS OF ESOPHAGEAL CANCER
Barium Swallow or Upper Gastrointestinal (GI) X-rays : -Esophageal cancers grow from the wall of the esophagus into the opening of the esophagus, creating a tumor or bump inside the esophagus. Barium in liquid form is used to coat the esophagus wall before the x-ray is taken, allowing the x-ray to show the esophagus clearly.
Upper Endoscopy for Esophageal Cancer : - Upper endoscopy is a procedure involving use of an endoscope, which is a flexible, very narrow tube with a video camera and light on the end. The patient is sedated to allow for this tube to pass through into the esophagus and stomach. The camera is connected to a television and doctor to sees abnormalities in the wall of the esophagus clearly. Endoscopy is important test for diagnosing esophageal cancer.
Endoscopic Ultrasound for Esophageal Cancer : - An endoscope with a small ultrasound probe attached to its end is used. The probe sends very sensitive sound waves that penetrate deep into tissues. The sound waves bounce off the normal tissues and the cancer are picked up by the probe and determine how deeply the tumor has invaded into the esophagus.
Thoracoscopy and Laparoscopy for Esophageal Cancer : -These procedures allow the doctor to see lymph nodes and other organs near the esophagus inside the chest (by thoracoscopy) or the abdomen (by laparoscopy) through a hollow lighted tube. The surgeon can operate instruments through the tube and remove lymph node samples and biopsy organs to see whether they contain cancer cells. It is often important to decide whether a person is likely to benefit from surgery.
Biopsy for Esophageal Cancer : - During an endoscopy or other procedure, the doctor will remove a small piece of tissue. This tissue is then examined by a pathologist who examines the tissue to determine whether cancer cells are present and if so, their type. It usually takes a couple of days to get the results of a biopsy.
· Surgery
: The surgical
procedure for removing the entire or a part of the esophagus depends on the
location and size of the tumor. There are a number of surgical procedures for
reaching to the esophagus. The surgical procedure can remove nearby soft
tissues, a section of the esophagus and the lymph nodes. The entire or a part
of the stomach can also be removed. The cancer is removed by making several
incisions in the abdomen and chest. In majority of cases, the stomach is pulled
up and is then joined with the remaining portion of the esophagus. Also, a part
of the intestine is used for connecting the stomach with the esophagus
remaining part. A part of large intestine or small intestine may also be used.
A part of the intestine is used when the stomach is removed for joining it with
the left over part of the esophagus to the small intestine.
·
Radio
Therapy : High-energy
radiation beams are targeted on the cancerous tissue in order to destroy it.
Radiotherapy is usually used in addition with either chemotherapy or surgery.
Radiotherapy can be categorized into two different types for treating
esophageal cancer that include :
·
Chemotherapy
: People with
esophageal cancer can also be treated with the help of chemotherapy. This
therapy makes use of certain drugs that helps in destroying the cancer cells.
The injection of these drugs is done into a vein (intravenous) that then
travels throughout the different parts of the body.
·
Radiofrequency
ablation (RFA) : In this
outpatient procedure, controlled bursts of radiofrequency energy burn away thin
layers of abnormal tissue on the surface of the esophagus, leaving healthy
tissue intact. Radiofrequency ablation takes about 45 minutes, and patients can
usually return to their normal activities the next day, though some patient may
experience chest pain and difficulty swallowing for about a week.
·
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