Cervical cancer originates in the cervix,
the lower part of the uterus (womb) and opens into
the vagina. It arises from the cells
present on the surface of the cervix.
Causes
Cervical cancer stands as the third most common
type of cancer in women. The main cause is HPV (Human Papilloma Virus), a
common virus that spreads through sexual intercourse.
Risk
factors
* Having premature sex
* Having more than one sexual partner
* Poor socioeconomic status
* Weakened immune system
Symptoms
* Vaginal bleeding after menopause
* Foul-smelling vaginal discharge
* Bleeding after intercourse
* Heavy menstrual or intermenstrual bleeding
Symptoms
of advanced cervical cancer
* Low backache
* Pain in the pelvis
* Exhaustion
* Excretion of urine or feces through the vagina
* Single swollen leg
* Loss of appetite
* Weight loss
Investigations
Screening tests
* For pre-cancer and cancer, Pap smear screens
are effective, though not for final diagnosis.
* Colposcopy is carried out if abnormal changes
are discovered. In this procedure, pieces of tissue are surgically removed (biopsy)
and sent to a laboratory for examination under magnification.
Diagnosis
tests
* Endocervical curettage (ECC) is used to
examine the opening of the cervix
* Cone biopsy
* Punch biopsy from cervical growth
Staging
tests
* Chest X-ray
* CT scan or MRI
* Cystoscopy
* Intravenous Pyelogram (IVP)
Treatment plan
The treatment of
cervical cancer depends on:
* Stage
* Size and shape
of the tumour
* The woman's
desire to have children in the future
* The woman's
age and general health
Treatment of early cervical cancers
* To ensure that
a woman can bear children in the future, removing the precancerous or cancerous
tissue without removing the uterus or harming the cervix, can cure early
cervical cancer.
* Pre-cancerous
conditions are curable when followed up and administered proper treatment.
* 92 per cent of
women with cervical cancer have a five-year survival rate.
* Radical
hysterectomy: The uterus and much of the surrounding tissues are removed,
including lymph nodes and the upper part of the vagina.
*Radiation
therapy: It is used in cases where the cancer has spread beyond the pelvis, or
cancer that has returned.
Radiation therapy is of two types:
* External
radiation therapy is like an X-ray and delivers radiation from a large
machine onto the part of the body where the
cancer is located.
* Internal
radiation therapy or brachytherapy entails placing a device filled with
radioactive material inside the woman's vagina.
* Intensity
Modulated Radiation Therapy (IMRT) and Image Guided Radiotherapy (IGRT) help
deliver radiation to the tumour and adjacent tissues sparing nearby normal
structures like urinary bladder, rectum and intestines and thus preventing long
term complications.
* Chemotherapy
uses drugs such as carboplatin, paclitaxel, 5-FU and cisplatin to destroy
cervical cancer. It is generally used along with radiation to sensitize the tumour.
Radiation and chemotherapy may be used before or after surgery.
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